SCREENING AND POTENTIAL OF MULTI-DRUG RESISTANCE IN GRAM NEGATIVE BACTERIA FROM HOSPITAL WASTEWATER

Articles in Press

Document Type : Research Note

Authors

1 Deparment of Biosceinces, Integral University, Lucknow

2 Department of Biosceinces, Integral University

Abstract

The antibiotic resistance profiles of Gram negative bacterial isolated from four different sampling sites of the hospital wastewater at Lucknow city was evaluated. Of the 200 Gram negative bacterial isolates tested, marked antibiotic resistances (over 90%) were observed for amoxicillin, methicillin, ampicillin, nalidixic acid and penicillin depending upon the sampling sites. All Gram negative bacterial isolates also showed multiple resistance patterns (2-13 antibiotics) in different combination of antibiotics. The MAR index ranges were found (0.01-0.86) indicating the high risk of environmental contamination. The findings indicated that pollution of aquatic environments from different sources of the city may have a significant contribution on the emergence and dissemination of resistance in Gram negative bacteria as well as other pathogenic bacteria in the hospital wastewater. This over use of antibiotics as well as other pharmaceuticals in the hospital and their introduction into the aquatic environment may have a potential public health risk.

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Iranian Journal of Science

Articles in Press, Accepted Manuscript
Available Online from 17 February 2016

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