Saberi, A. (2015). Efficient synthesis of Benzimidazoles using zeolite, alumina and silica gel under microwave irradiation. Iranian Journal of Science and Technology (Sciences), 39(1), 7-10. doi: 10.22099/ijsts.2015.2884
A. Saberi. "Efficient synthesis of Benzimidazoles using zeolite, alumina and silica gel under microwave irradiation". Iranian Journal of Science and Technology (Sciences), 39, 1, 2015, 7-10. doi: 10.22099/ijsts.2015.2884
Saberi, A. (2015). 'Efficient synthesis of Benzimidazoles using zeolite, alumina and silica gel under microwave irradiation', Iranian Journal of Science and Technology (Sciences), 39(1), pp. 7-10. doi: 10.22099/ijsts.2015.2884
Saberi, A. Efficient synthesis of Benzimidazoles using zeolite, alumina and silica gel under microwave irradiation. Iranian Journal of Science and Technology (Sciences), 2015; 39(1): 7-10. doi: 10.22099/ijsts.2015.2884
Efficient synthesis of Benzimidazoles using zeolite, alumina and silica gel under microwave irradiation
Chemistry Department, Payame Noor University, 19395-4697 Tehran, Iran
Abstract
As benzimidazole ring is an important pharmacophore in modern drug discovery and benzimidazoles are very important intermediates in organic reactions, the preparation of benzimidazoles has gained considerable attention in recent years. Here, a comparative study on the synthesis of benzimidazoles from aromatic, aliphatic and heterocyclic carboxylic acid, benzonitrile and o-phenylenediamine under microwave irradiation and solvent-free conditions is catalyzed by alumina, silica gel and zeolite is presented. All the synthesized compounds are characterized by 1H-NMR, IR, Mass and CHNS analysis.
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