SCREENING OF SELECTED PLANTS GROWING IN IRAN FOR ANTIMICROBIAL ACTIVITY

Document Type: Regular Paper

Authors

1 Medicinal & Natural Product Chemistry Research Centre, Shiraz University of Medical Sciences, Shiraz, I. R. of Iran 2Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, I. R. of Iran

2 Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, Shiraz, I. R. of Iran

3 Medicinal & Natural Product Chemistry Research Centre, Shiraz University of Medical Sciences, Shiraz, I. R. of Iran

4 Medicinal & Natural Product Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, I. R. of Iran

Abstract

The antimicrobial activity of methanolic extracts from different parts of 11 indigenous wild plant
species used in traditional medicines of Iran were tested against nine species of microorganisms: Escherichia
coli, Staphylococcus aureus, Staphylococcus epidermis, Pseudomonas aeruginosa, Klebsiella pneumoniae,
Salmonella typhi, Bacillus subtilis, Aspergillus niger and Candida albicans. The antimicrobial efficacy was
determined using the disk diffusion (0.5, 1, 2 and 4 mg/disk) and minimal inhibition concentration (MIC)
method. Among the 11 tested herbs, 9 plants showed antimicrobial activity against one or more species of
microorganism. The most active antimicrobial plants were Stachys obtusicrena, Anvillea garcinii, Salvia
species, Otostegia persica and Teucrium persicum.

Keywords