TY - JOUR ID - 2563 TI - Friedel–Crafts acylation of aromatic compounds JO - Iranian Journal of Science JA - ISTT LA - en SN - 2731-8095 AU - Hajipour, A. R. AU - Nazemzadeh, S. H. AU - Karimi, H. AD - Pharmaceutical Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan 84156, Iran Y1 - 2014 PY - 2014 VL - 38 IS - 4 SP - 463 EP - 471 KW - Iron zirconium phosphate KW - nanoparticles KW - acylation KW - Solvent-free KW - solid catalyst DO - 10.22099/ijsts.2014.2563 N2 -   An efficient method for the Friedel–Crafts acylation of a wide range of aromatic compounds in good to excellent yields under solvent-free conditions, using iron zirconium phosphate (ZPFe) was investigated. The catalyst is easy to prepare and shows interesting catalytic properties. The catalyst was characterized by some instrumental techniques such as XRD, ICP-OES, SEM and TEM. A wide variety of benzene derivatives reacted easily with benzoyl chloride and some of its derivatives to afford the corresponding aromatic ketones in clean and good yields with the para isomer predominating typically using 3mol% of catalyst. The use of inexpensive materials, simple and clean work-up, short reaction times in most cases and good yields are the main advantages of this method. This work introduces a new application of this catalyst, not described in the literature until now. Also, the catalyst can be recovered and reused for three times without a significant loss in its activity and selectivity. UR - https://ijsts.shirazu.ac.ir/article_2563.html L1 - https://ijsts.shirazu.ac.ir/article_2563_12abf4a75c21b1b2ed8a550b3c2bbe21.pdf ER -